Question

Sickle cell anemia is example of

Answer 1

$\huge\bold\red{Heya!!!}$

$\bold{constitutional\: disease\: of\: hemoglobin }$

Sickle cell anemia, an example of a constitutional disease of hemoglobin]. Sickle cell anemia is a congenital haemolitic anemia. The replacement of the hydrophilic glutamine residue at the 6 position of the beta chain by the hydrophobic valine leads to severe conformation change in the molecule resulting in sickling.

Answer 2

Sickle cell anemia is a example of autosomal recessive disorder. This disorder is caused due to the abnormal formation of the haemoglobin.

Let's consider HbA is normal hemoglobin but after mutation when it becomes HbS then it is considered as the mutant for sickle cell anemia.

Some other important points about sickle cell anemia are as follows :-

1. It is type of qualitative disorder.

2. It is a disease of the 11th chromosome.

3. This disorder is caused in the β chain.

4. It is a type of point mutation.

5. In this glutamic acid is substituted by valine