Question

Significance of binding affinity in molecular docking

Answer 1

Explanation:

Occupying these regions with a ligand molecule results in both more favorable enthalpy and entropy of binding.

The reason for this gain in binding affinity is the fact that the increased protein-ligand interaction surface results in stronger van der Waals interaction.

Answer 2

Answer:

Occupying these regions with a molecule results in both more favorable enthalpy and entropy of binding The reason for this gain in binding affinity is the fact that the increased protein- interaction surface results in stronger van der Waals interaction.