Smallest virus replicate autonomously in eukaryotic cell is
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Porcine circovirus is the smallest virus which replicate autonomously in eukaryotic cell.
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It is a group of 'single stranded DNA' which is non-enveloped with an 'unsegmented circular genome'. They have viral capsid of approximately 17 nm.
They replicate in the nucleus of infected cells and use the host polymerase to enhance their multiplication. There are two types of PCV: PCV -1 and PCV – 2. Both show a 'high degree of sequence identity' and a similar gene organization.
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