Question

Specific inhibition of huntingtons disease gene expression by sirnas in cultured cells.

Answer 1

The binding of an inhibitor can stop a substrate from entering the enzyme's active site and/or hinder the enzyme from catalyzing its reaction. Inhibitor binding is either reversible or irreversible. Irreversible inhibitorsusually react with the enzyme and change it chemically (e.g. via covalent bond formation).