starch is an example of following category of pharmaceutical aid. (A) binding (B) Disintegrating agent
Answers
Answer:
Starch is an example of a natural polymer. A polymer is a long and repeating chain of the same molecule stuck together. Starch is a long-chain polymer of glucose molecules joined together. As the plant adds one glucose molecule to the starch polymer, one molecule of water is released.
Explanation:
Answer:
Starch is an example of following category of pharmaceutical aid:
- Binder
- Disintegrant
- Diluent
- Absorbents
- Glidant/lubricant
- Modified starches
Explanation:
Starch is one of the most widely used pharmaceutical ingredients because it is one of the few natural products, with minimal processing, that meets most of the requirements for excipients. It is non-toxic, odorless, inexpensive, widely available, and biocompatible.
In its natural form, starch is used in the creation of several types of food where its functions depend on the specific type of tissue.
Binder
Starch is widely used as a binder in the wet granulation process of bulking and screening which is an important step in the production of tablets, capsules, and other solid forms. The granulation process is used to improve the flow of highly targeted APIs. In this process, starch is used as a water binder to create agglomerates with good flow properties. The paste made by heating a suspension of starch is used to "stick together" the particles in the composition to form larger agglomerates that reduce cohesiveness and encourage in the flow.
Disintegrant
A disintegrant is an excipient included in a pharmaceutical formulation to achieve the breaking of solids such as tablets or granules into smaller particles. The opening is an important step in the process of release and absorption because it represents a large part of the drug that is easily and quickly reached the end. This increases the process of dissolution, drug release, and absorption to achieve the desired therapeutic effect of the drug. Starch is a simple and easy-to-use solvent that is thought to do this job because its particles swell in the presence of water which leads to the elimination of solid bridges and binders. other solids in the dosage form. The degree of swelling is a function of the source or type of starch that reflects the relative proportion and proportion of amylose and amylopectin in the starch.
Diluent
Some drugs are used at very low doses so it is very difficult to manufacture them and finally store them in tablets and other forms. In such cases, inert substances that do not affect the pharmacological effect of the drug can be included in the formulation to increase it to allow normal processes. Because it is dark, odorless, and digestible, starch is used for this purpose.
Absorbents
Starch is hygroscopic and can hold up to 10-17% moisture compared to normal atmospheric conditions.
Glidant/lubricant
Starches have been studied for use as lubricants and glidants [9] due to their slippery nature and ability to adhere to surfaces.
Modified starches
In its natural form, the use of starch is limited due to its inability to withstand certain working conditions such as high temperature, different pH, free-thaw cycles, its nature for retrogradation and decomposition, and brittleness.
For more such questions:
https://brainly.in/question/1150390
#SPJ1