Question

Starting material for synthesis of Benzamide is A). Phenol B) Acetic acid C) Benzene D) None​

Answer 1

Explanation:

(c) benzene

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Answer 2

Answer:

The correct option is (C) Benzene.

Explanation:

• Benzamide compounds are important building blocks in chemical synthesis and are used as substructures in a wide range of pharmaceuticals.
• Hydrolysis of aromatic nitriles, interconversions of carboxylic acid derivatives, oxime rearrangement, aminocarbonylation, and other methods have all been used to make benzamides.
• Friedel-Crafts reactions of isocyanates have also been used to make aromatic amides, particularly 2° amides.
• Trimethylsilylisocyanate and chlorosulfonylisocyanate, two chemicals that are not widely available and are potentially hazardous, have previously been used to make primary benzamides.
• We recently reported a low yield (12%) synthesis of benzamide using a superacid-catalyzed cyanamide-benzene reaction.

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