state and explain krebs cycle with diagram
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The TCA cycle is initiated with the condensation of the acetyl-CoA with oxaloacetate to form citrate. The citrate is converted to isocitrate via addition of water across the double bond of cis-aconitate, the isocitrate is dehydrogenated to oxalosuccinate and the oxalosuccinate is decarboxylated to α-ketoglutarate.
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The TCA cycle is initiated with the condensation of the acetyl-CoA with oxaloacetate to form citrate. The citrate is converted to isocitrate via addition of water across the double bond of cis-aconitate, the isocitrate is dehydrogenated to oxalosuccinate and the oxalosuccinate is decarboxylated to α-ketoglutarate
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