Question

State the role of pancreatic juice in digestion of proteins.

Answer 1

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❇️ Pancreatic juice contains a variety of inactive enzymes such as trypsinogen, chymotrypsinogen, and carboxypeptidases.

❇️ These enzymes play an important role in the digestion of proteins.

✔️Physiology of protein-digestion by pancreatic enzymes:

❇️ The enzyme enterokinase is secreted by the intestinal mucosa. It activates trypsinogen into trypsin.

❇️ Trypsin then activates the other enzymes of pancreatic juice such as chymotrypsinogen and carboxypeptidase.

❇️ Chymotrypsinogen is a milk-coagulating enzyme that converts proteins into peptides.

❇️ Carboxypeptidase acts on the carboxyl end of the peptide chain and helps release the last amino acids. Hence, it helps in the digestion of proteins.

❇️ Thus, in short, we can say that the partially-hydrolysed proteins present in the chyme are acted upon by various proteolytic enzymes of the pancreatic juice for their complete digestion.

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Answer 2

The role of Pancreatic juice in the digestion of proteins:

• "Pancreatic juice" is a juice that is produced in the pancreas and it plays a very vital role in the digestion of proteins.
• Pancreatic juice contains $\mathrm{NaHCo}_{3}$ which neutralizes the acid chyme that contains in the stomach and maintains the alkaline medium in the small intestine.
• The hydrolytic enzymes of the pancreatic juice take place in protein digestion.
• The endocrine part of the pancreas secrets different hormones such as "insulin, glucagon and somatostatin".

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