Question

Storage condition and stability of official vaccine

Answer 1

Answer:

Vaccine Storage and Handling

There are few immunization issues more important than

the appropriate storage and handling of vaccines. The

success of efforts against vaccine-preventable diseases

is attributable in part to proper storage and handling of

vaccines. Vaccines exposed to temperatures outside the

recommended ranges can have reduced potency and

protection. Storage and handling errors can cost thousands

of dollars in wasted vaccine and revaccination. Errors can

also result in the loss of patient confidence when repeat

doses are required. It is better to not vaccinate than to

administer a dose of vaccine that has been mishandled.

Vaccine management, including proper storage and

handling procedures, is the basis on which good immuniza

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tion practices are built.

Vaccines must be stored properly from the time they

are manufactured until they are administered. Proper

maintenance of vaccines during transport is known as the

cold chain. A proper cold chain is a temperature-controlled

supply chain that includes all equipment and procedures

used in the transport and storage and handling of vaccines

from the time of manufacturer to administration of the

vaccine. By following a few simple steps and implementing

best storage and handling practices, providers can ensure

that patients will get the full benefit of vaccines they

receive.

Vaccine Storage Temperatures

Vaccines are fragile. They must be maintained at the

temperatures recommended by vaccine manufacturers

and protected from light at every link in the cold chain.

Most live virus vaccines tolerate freezing temperatures, but

deteriorate rapidly after they are removed from storage.

Inactivated vaccines can be damaged by exposure to

temperature fluctuations (e.g., extreme heat or freezing

temperatures). Potency can be adversely affected if

vaccines are left out too long or exposed to multiple

temperature excursions (out-of-range temperatures) that

can have a cumulative negative effect. It is a good idea to

post a sign on the front of the storage unit(s) indicating

which vaccines should be stored in the freezer and which

should be stored in the refrigerator.

Freezer

All varicella-containing vaccines should be stored in a

continuously frozen state at the manufacturer recommended freezer temperature until administration. All

varicella-containing vaccines (VAR, Varivax; ZOS, Zostavax;

and MMRV, ProQuad) should be stored between between

-58°F and +5°F (-50°C and -15°C).

The measles, mumps, rubella vaccine (MMR) can be stored

either in the freezer or the refrigerator. Storing MMR in the

freezer with MMRV may help prevent inadvertent storage of

MMRV in the refrigerator.

Answer 2

The vaccines are the chemical formulations used to provide immunity against the disease causing pathogen.

Explanation:

• Storage of vaccines: The vaccine must be stored in appropriate temperature as suggested by the manufactures of the vaccines. The vaccines must be protected from the action of heat and light. Most live vaccines can tolerate the freezing temperatures.
• Stability of vaccines: The vaccines can remain stable for long by controlling the handling, testing and storage conditions of the vaccine. For maintaining the stability potency, purity and identity of the vaccine must be retained.

Learn more about vaccine:

What is vaccine and vaccination: https://brainly.in/question/12432410