Structural control of crystal nuclei by an eggshell protein
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Metadynamics simulations show that the eggshell protein ovocleidin‐17 induces the formation of calcite crystals from amorphous calcium carbonate nanoparticles. Multiple spontaneous crystallization and amorphization events were simulated; these simulations suggest a catalytic cycle that explains the role of ovocleidin‐17 in the first stages of eggshell formation (the picture shows one intermediate of this cycle).
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The results show that the chicken eggshell protein ovocleidin‐17 can facilitate a transition from amorphous particle to calcite crystal. ... This catalytic cycle provides a mechanism for forming the polycrystalline mammillary caps that are deposited on the organic membrane as the first stage of eggshell formation.
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