Question

Subcellular distribution of the inositol 1,4,5-trisphosphate receptors: functional relevance and molecular determinants

Answer 1

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The inositol 1,4,5-trisphosphate receptor (IP3R) is an intracellular Ca2+ channel that is for the largest part expressed in the endoplasmic reticulum. Its precise subcellular localization is an important factor for the correct initiation and propagation of Ca2+ signals.....