submucosa is a composed of tissue
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The submucosa, located between the outermost layer of the mucosa and the muscularis externa, is made of connective tissue and several different cell types that include fibroblasts, lymphocytes, eosinophils, macrophages, plasma cells, and mast cells.
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The submucosa consists of a dense irregular layer of connective tissue with large blood vessels, lymphatics, and nerves that branch into the mucosa and muscularis externa. ... In the gastrointestinal tract, the submucosa is the layer of dense irregular connective tissue or loose connective tissue that supports the mucosa.
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