sulphonamides are in action
Answers
Answer:
Mode of action: Inhibition of other metabolic processes. Sulfonamides interfere with folic acid synthesis by preventing addition of para-aminobenzoic acid (PABA) into the folic acid molecule through competing for the enzyme dihydropteroate synthetase.
Mode of action: Inhibition of other metabolic processes. Sulfonamides interfere with f...
Effect on bacteria: Bacteriostatic
Spectrum of activity: Broad-spectrum; affects Gram-positive and many Gram-negative ...
Example: Sulfadiazine, sulfamethoxazole, sulfadoxine
Answer:
Sulfanomides Mode of Action. Antibacterial sulfonamides target a bacterial metabolic pathway as competitive inhibitors of the enzyme dihydropteroate synthetase, DHPS. Dihydropteroate synthetase activity is vital in the synthesis of folate, and folate is required for cells to make nucleic acids, such as DNA or RNA