Question

Suppose that Bill's genotype is (Hh) and his wife Sharon is (hh). What are the chances that his daughter, Grace, will also have Huntington's?

Answer 1

Explanation:

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Answer 2

The chances of Grace getting the disease is - 50%

Huntington's disease is an autosomal dominant disorder which results in breaking of nerve cells.

It is an autosomal disease which means that it is not present on X or Y chromosome and hence has equal chances of being transmitted.

It is a dominant disorder which means presence of its only one dominant gene can cause the expression of disease.

The alleles that will form are -

Bill - H and h, Sharon - h and h.

Alleles that will form on combination are - Hh, Hh, hh and hh.

The results clearly show 50% chance of disease occurrence