Biology, asked by farhan9114, 1 year ago

Synthesis and biological evaluation of angiogenesis inhibitors: aromatic enones and dienone analogues of curcumin

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Answered by generalRd
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Systemic literature searches were carried out using following databases; Pubmed, Scifinder, Scopus, ScienceDirect, Medline, Embase, Google Scholar and Web of Science using the key words, turmeric, C. longa, curcuminoids, curcumin, bioavailability, bio-enhancer, pharmacokinetic, phytosome, liposome, analogs, metal complexes and nanoparticles (NPs) and a library search for articles published in peer-reviewed journals and also locally available books.

3. Discovery of curcumin

Curcumin is the active ingredient of the dietary spice turmeric and is extracted from the rhizomes of C. longa, a plant in the Zingiberaceaefamily. It was first discovered about two centuries ago when Vogel and Pelletier reported the isolation of a “yellow coloring matter” from rhizomes of C. longa and named it curcumin.
 It is characterized by Milobedeska et al  and first synthesized by Lampe et al.

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