Synthetic importance of hell volhard zelinsky reaction
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The synthetic importance of the HVZ reaction is given below.
- Hell Volhard Zelinsky reaction is used to halogenate carboxylic acids at alpha carbon.
- Phosphorous tribromide is the catalyst used here.
- Phosphorous and bromine react with each other to give Phosphorous tribromide
- In the first step carboxylic acid gets converted into acyl bromide.
- Tautomerism exists between acyl form and enol form.
- The enol form is brominated to give alpha Bromo carboxylic acid.
- HVZ reaction is used in the synthesis of amino acids
- It is also used for the bromination of carboxylic acid.
- #SPJ3
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