Question

Tetracycline is an antibiotic that blocks tRNA from entering the ribosome and associating with mRNA. If tetracycline were added to the cytoplasm of a eukaryotic cell, which types of proteins would be made?(1 point)
No proteins will be made if tRNA cannot bind to mRNA


Only proteins that will be inserted into a membrane


Only proteins that will be exported outside of the cell


Only proteins that function in the cytoplasm of the cell

Answer 1

Answer:

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Answer 2

The correct solution is option. a, No proteins will be made if tRNA cannot bind to mRNA

• Tetracyclines are the first broad-spectrum antibiotics found to be effective against both gram-negative and gram-positive bacteria.
• Antibiotics are used to treat bacterial diseases without affecting the eukaryotic cell but kill the disease-causing bacterial cell.
• Antibiotics have many targets in the bacterial cell, but ≅40% of the discovered antibiotics are the inhibitors of the translation machinery.
• Tetracycline is an antibiotic that binds a component of the translation apparatus and inhibits its function in the prokaryotic cell and yet no protein is formed.
• The molecular target of the tetracycline is the A-site of the 30s ribosomal subunit of bacteria.
• It inhibits the aminoacyl-tRNA binding to the A-site of the ribosome and prevents the translocation of A-site tRNA to P-site.
• Tetracycline is often used in treating sexually transmitted bacterial diseases like syphilis, Gonorrhea, Chlamydia, etc.