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Nucleus was first observed by Leeuwenhoek in the RBCs of fishes.
The term 'Nucleus' was coined by Robert Brown in 1831.
Nucleus is a double membrane bound dense protoplasmic body.
It encloses the genetic information of the cell which means that the genetic material (DNA or RNA) is present in it.
It is absent in prokaryotes and mature RBCs in case of eukaryotes.
Depending upon the number of nucleus, a cell may be uninucleate, binucleate or multinucleate.
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The main function of the cell nucleus is to control gene expression and mediate the replication of DNA during the cell cycle. The nucleus is an organelle found in eukaryotic cells. Inside its fully enclosed nuclear membrane, it contains the majority of the cell's genetic material.
- The cell nucleus contains all of the cell's genome, except for the small amount of mitochondrial DNA, organized as multiple long linear DNA molecules in a complex with a large variety of proteins, such as histones, to form chromosomes. The genes within these chromosomes are structured in such a way to promote cell function. The nucleus maintains the integrity of genes and controls the activities of the cell by regulating gene expression—the nucleus is, therefore, the control center of the cell.
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