Question

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Write the steps to prepare Aspirin from salycylic acid!??
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Answer 1

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SYNTHESIS OF ASPIRIN (acetylsalicylic acid)

• Place 2.0 g (0.015 mole) of salicylic acid in a 125-mL Erlenmeyer flask.
• Add 5 mL (0.05 mole) of acetic anhydride, followed by 5 drops of conc. ...
• Heat the flask gently on the steam bath for at least 10 minutes.
• Allow the flask to cool to room temperature.

Answer 2

Answer:

SYNTHESIS OF ASPIRIN (acetylsalicylic acid)

1. Place 2.0 g (0.015 mole) of salicylic acid in a 125-mL Erlenmeyer flask.
2. Add 5 mL (0.05 mole) of acetic anhydride, followed by 5 drops of conc. ...
3. Heat the flask gently on the steam bath for at least 10 minutes.
4. Allow the flask to cool to room temperature.

The synthesis of aspirin is known in organic chemistry as an esterification reaction. This is a substitution reaction in which an alcohol (the –OH group in salicylic acid) reacts with acetic anhydride to form an ester, aspirin.