Question

$\sf{\underline{\huge{Question:}}}$

What are base stacking interactions?
Explain in detail!!

Answer 1

Base stacking interactions :

Base stacking is used to analyse the structure of DNA on the basis of energetics of the base stacking interactions.

➨ The most important for C.G base pairs which are highly polarized is electrostatic interactions between stomic charges.

➨ Subtle sequence-dependent effects are caused by electrostatic interactions between the partial atomic changes in one base-pair and out of plane π electron density on another.

➨ In general, Electrostatic interactions causes non-zero side.

➨ At the sites of replication this sequences - Buckle, propeller twist and role of TATA.

Answer 2

Answer:

Base-stacking interactions are hydrophobic and electrostatic in nature, and depend on the aromaticity of the bases and their dipole moments. Base-stacking interactions in nucleic acid double strands are partly inter-strand and partly intra-strand in nature

Explanation: