The beaded appearance in Rough - Endoplasmic reticular is due to the presence
Nucleosomes.
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Rough endoplasmic reticulum (RER), series of connected flattened sacs, part of a continuous membrane organelle within the cytoplasm of eukaryotic cells, that plays a central role in the synthesis of proteins. The rough endoplasmic reticulum (RER) is so named for the appearance of its outer surface, which is studded with protein-synthesizing particles known as ribosomes. This feature distinguishes it superficially and functionally from the other major type of endoplasmic reticulum (ER), the smooth endoplasmic reticulum (SER), which lacks ribosomes and is involved in the synthesis and storage of lipids. RER occurs in both animal and plant cells.
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