The body's natural defense systems work to keep the body healthy.
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Usually, the skin prevents invasion by microorganisms unless it is damaged (for example, by an injury, insect bite, or burn).
Mucous membranes, such as the lining of the mouth, nose, and eyelids, are also effective barriers. Typically, mucous membranes are coated with secretions that fight microorganisms. For example, the mucous membranes of the eyes are bathed in tears, which contain an enzyme called lysozyme that attacks bacteria and helps protect the eyes from infection.
The airways filter out particles that are present in the air that is inhaled. The walls of the passages in the nose and airways are coated with mucus. Microorganisms in the air become stuck to the mucus, which is coughed up or blown out of the nose. Mucus removal is aided by the coordinated beating of tiny hairlike projections (cilia) that line the airways. The cilia sweep the mucus up the airways, away from the lungs.
The digestive tract has a series of effective barriers, including stomach acid, pancreatic enzymes, bile, and intestinal secretions. These substances can kill bacteria or prevent them from multiplying. The contractions of the intestine (peristalsis, which moves contents of the bowel through the digestive tract), and the normal shedding of cells lining the intestine help remove harmful microorganisms.
The urinary tract also has several effective barriers. The bladder is protected by the urethra, the tube that drains urine from the body. In males, the urethra is long enough that bacteria are seldom able to pass through it to reach the bladder, unless the bacteria are unintentionally placed there by catheters or surgical instruments. In females, the urethra is shorter, occasionally allowing external bacteria to pass into the bladder. In both sexes, when the bladder empties, it flushes out any bacteria that reach it.
The vagina is normally acidic. The acidity of the vagina prevents harmful bacteria from growing and helps maintain the number of protective bacteria.
The Blood
The body also defends against infection by increasing the number of certain types of white blood cells (neutrophils and monocytes), which engulf and destroy invading microorganisms. The increase can occur within several hours, largely because white blood cells are released from the bone marrow, where they are made. The number of neutrophils increases first. If an infection persists, the number of monocytes increases. The blood carries white blood cells to sites of infection.
The number of eosinophils, another type of white blood cell, increases in allergic reactions and many parasitic infections, but usually not in bacterial infections.
However, certain infections, such as typhoid fever, viral infections, and bacterial infections that overwhelm the immune system, can lead to a decrease in the white blood cell count.
Inflammation
Any injury, including an invasion by microorganisms, causes inflammation in the affected area. Inflammation, a complex reaction, results from many different conditions. The damaged tissue releases substances that cause inflammation and that direct the immune system to do the following:
Wall off the area
Attack and kill any invaders
Dispose of dead and damaged tissue
Begin the process of repair
However, inflammation may not be able to overcome large numbers of microorganisms.
During inflammation, the blood supply increases, helping carry immune cells to the affected area. An infected area near the surface of the body becomes red and warm. The walls of blood vessels become more porous, allowing fluid and white blood cells to pass into the affected tissue. The increase in fluid causes the inflamed tissue to swell. The white blood cells attack the invading microorganisms and release substances that continue the process of inflammation.
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they do work in their benefit