Question

The cell wall of scleroderma tissue are thickened due to deposition of which material

Answer 1

Answer:

extracellular collagen type I

In scleroderma, the dermis is infiltrated by T lymphocytes, causing abnormal fibroblasts activation, which leads to increased production of extracellular collagen type I. This increase in collagen causes skin thickening and tightening, which is the main manifestation of this disease.

Answer 2

Explanation:

The thickened skin in scleroderma is caused by overproduction of collagen, which is the basic component of scar tissue. Abnormal accumulation of collagen is called fibrosis. Collagen is a normal part of skin and many organs.