Question

The chemical method developed by
was instrumental in synthesizing RNA molecules with
defined combination of bases.
(a) Marshall Nirenberg
(b) George Gamow
(c) Har Gobind Khorana (d) F.H. C. Crick
​

Answer 1

Answer:

Option c) Har Gobind Khorana

Answer 2

Answer:

The chemical method developed by Har Gobind Khorana was instrumental in synthesizing RNA molecules with different combinations of bases.

Explanation:

• Each of the 64 potential triplets (codons) was created by Khorana and his colleagues by synthesizing polynucleotides with known chemical compositions. 
• Khorana overcame many challenges in the chemical synthesis of polyribonucleotides by combining synthetic and enzymatic methods.
• His work provided conclusive evidence of codon assignments and defined some codons that were unknown before.
• The research of Khorana also demonstrated that three nucleotides are required to specify an amino acid, that messenger RNA information is read in only one direction, and that the codons do not overlap.

#SPJ3