Question

The conformational change in an enzyme after the substrate is bound that allows the chemical reaction to proceed, can be explained by
A.induced fit
B. transition
C. fit and fine
D. Pasteur

Answer 1

HEY MATE HERE IS YOUR ANSWER

OPTION. A

Answer 2

The conformational change in an enzyme after the substrate is bound that allows the chemical reaction to proceed, can be explained by the Induced fit Theory. (option - A)

• The induced-fit theory says that when a substrate binds to the enzyme, a conformational change in the enzyme induces the production of product or catalysis of the reaction.
• The lock and key mechanism is given by Fischer, states that the substrate must fit into the active site of the enzyme.
• The induced-fit theory was given by Koshland that postulated that along with substrate being conformationally similar to the active site of the enzyme, induces a conformational change in the enzyme to fully fit the substrate in order to align the catalytic site and functional structure to proceed catalysis.
• The enzyme-substrate complex is called the transition state.