The cytoplasm of a neuron contains many negatively charged proteins, which give the cell a slightly negative charge at rest. What do you think happens to this charge when the neuron is stimulated?
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During a stimulus, there is an influx of Na+ ions into the cells. This causes the inside of the cell to develop a more positive charge compared to outside the cell. So, the cell attains a more positive charge when it is stimulated.
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In the stimulation, there’s an influx of sodium ions. So, the cell acquires a positive charge. But when the positively charged potassium ions move outside of the cell, the neuron returns to its previous state.
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