Question

The deoxyadenosine methylase (dam) enzyme of E. coli mediates the post-replicative NA. The SeqA protein of E. coli binds with hig methylation of newly synthesized D affinity to hemi-methylated DNA to control the timing of the initiation of DNA replication. Suppose that the gene encoding the dam methylase acquired a mutation that dramatically decreased the amount of methylase activity in the cell. How would the timing of initiation of the next round of DNA replication be affected by the mutation? Would the time required before the next round of DNA synthesis increase or decrease?

A. It would decrease due to more persistent SeqA binding
B. It would increase due to less persistent SeqA binding
C. It would decrease due to less persistent SeqA binding
D. It would increase due to more persistent SeqA binding-
E. It would not be affected.

Answer 1

Option E.

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