The fluidity of plasma membrane is regulated by
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If unsaturated fatty acids are compressed, the “kinks” in their tails push adjacent phospholipid molecules away, which helps maintain fluidity in the membrane.
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Cholesterol acts as a bidirectional regulator of membrane fluidity because at high temperatures, it stabilizes the membrane and raises its melting point, whereas at low temperatures it intercalates between the phospholipids and prevents them from clustering together and stiffening.
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