Question

The following reaction catalysed by phosphoglucomutase
occurs during breakdown of glycogen:
glucose 1-phosphate ~ glucose 6-phosphate.
A reaction is started by adding phosphoglucomutase to
0.04 gmol glucose 1-phosphate in 1 litre solution at 25~
The reaction proceeds to equilibrium at which the concentration of glucose 1-phosphate is 0.002 M and the concentration
of glucose 6-phosphate is 0.038 M.
(a) Calculate the equilibrium constant.
(b) What is the theoretical yield?
(c) What is the yield based on amount of reactant supplied?

Answer 1

Answer:

a.calculate the eqlibrioum constant.

Explanation:

rate of forward reaction =rate of back ward reaction.

Answer 2

The value of a chemical reaction's reaction quotient at chemical equilibrium is known as the equilibrium constant.

Multiply the ratio by the limiting reactant's mole quantity. The answer is the theoretical yield of the desired product in moles.

Explanation:

Only in the presence of alpha-D-glucose 1,6-bisphosphate can maximum activity occur. This bisphosphate is a chemical intermediate, created when a phosphate residue from the enzyme is transferred to the substrate, but its dissociation from the enzyme complex is significantly slower than the total isomerization. EC 5.4.2.5, phosphoglucomutase, catalyses the interconversion of 1-phosphate and 6-phosphate isomers of several additional alpha-D-hexoses, as well as the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate (glucose-cofactor).