Question

The graphic shows the citric acid cycle. mc029-1.jpg During the citric acid cycle, what happens to acetyl-CoA?

Answer 1

The acetyl-CoA is an essential molecule in metabolism, utilized in various biochemical reactions. Its prime role is to conduct the atoms of carbon within the acetyl group to the Krebs cycle or citric acid cycle to be oxidized for the production of energy.  

For each acetyl CoA, which enters the citric acid cycle, two molecules of carbon are discharged in the reactions, which are coupled with the generation of NADH molecules from the reduction of NAD+ molecules.  

Answer 2

Acetyl CoA links glycolysis and pyruvate oxidation with the citric acid cycle. ... For each acetyl CoA that enters the citric acid cycle, two carbon dioxide molecules are released in reactions that are coupled with the production of NADH molecules from the reduction of NAD+ molecules.