The harmful allele of sickle cell anemia has not been eliminated from human population. Such afflicted people derive some other benefits. Discuss.
Answers
Answer:due to elimination of glutamic acid the RBC take the shape of a long sickle
Explanation:due to this the Africans are most benefited as they are resistant to plasmodium falciparum thus immune to malaria
Answer:
The harmful alleles get eliminated from population over a period of time, yet sickle cell anaemia is persisting in human population because SCA is a harmful condition which is also a potential saviour from malaria.
Those with the benign sickle trait possess a resistance to malarial infection. The pathogen that causes the disease spends part of its cycle in the red blood cells and triggers an abnormal drop in oxygen levels in the cell. In carriers, this drop is sufficient to trigger the full sickle-cell reaction, which leads to infected cells being rapidly removed from circulation and strongly limiting the infection’s progress. These individuals have a great resistance to infection and have a greater chance of surviving outbreaks. This resistance to infection is the main reason the SCA allele and SCA disease still exist. It is found in greatest frequency in populations where malaria was and is still often a serious problem