The incompatibility forms a natural barrier
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Gametic incompatibility is a natural prezygotic reproductive isolation mechanism. Prezygotic isolation mechanisms are defined as the mechanisms which prevent the formation of zygote between incompatible organisms. In gametic incompatibility, if the sperm and ova are from different species then they do not recognize each other and hence do not fuse to form the zygote. Hence, incompatibility act as a natural barrier for fusion of gametes to prevent reproduction between individuals of different species.
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