Question

The leading strand of a DNA molecule has the following sequence:

5’-CGCATGTAGCGA-3’

Write down sequences complementary to the leading strand shown above.

Answer 1

Answer:

DNA, Adenine (A) pairs with Thymine (T) and Guanine (G) pairs with Cytosine (C).

Hence, on replication of DNA in M phase, complementary nucleotides for each base pair will be added as follows:

A - T

T - A

G - C

C - G

Since replication occurs in 5'-3' direction, so the complementary strand will be formed in 3'-5' direction.

Hence the sequence of complementary strand formed upon replication will be: 3'-TGACGGATACGA-5'

So, the correct answer is 3'-TGACGGATACGA-5'.