The major effect of genetic drift is:
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Drift leads to an increase in homozygosity for diploid organisms and causes an increase in the inbreeding coefficient. Drift increases the amount of genetic differentiation among populations if no gene flow occurs among them. Genetic drift also has two significant longer-term evolutionary consequences.
The major effect of genetic drift can be specialization. Genetic drift can cause allele frequencies to change at random. ... In very small populations, genetic drift can also cause alleles that are a little harmful to become fixed
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