Question

The major parameters which influences the biological activity of compounds are

a.
Lipophilicity, steric effects & electronic effect

b.
Hydrophilicity, inductive effect & chemical structure

Ос.
Hydrophobicity, mesomeric effect & resonance effect

d.
Lipophilicity, steric effect& resonance effect​

Answer 1

Answer:

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Inductive Effect, Electromeric Effect, Resonance Effects, and Hyperconjugation

Electronic factors that influence organic reactions include the inductive effect, electromeric effect, resonance effects, and hyperconjugation. These electronic factors involve organic molecules, most of which are made from a combination of the following six elements: carbon, hydrogen, nitrogen, oxygen, phosphorus, and sulfur (known collectively as CHNOPS). Yet, the limited number of building blocks does not prevent organic compounds from taking on diverse properties in their physical characteristics and chemical reactivity. The subtle differentiation of various compounds in organic chemistry is essential for the biological functions of the molecules and creates a wide variety of reactions.

Part of this variety in organic chemistry stems from differences in electron behavior when elements other than carbon and hydrogen participate in molecular bonds. For example, the three compounds pictured above have similar formula units and structures, but react very differently from one another because of these electronic factors. Varying electronegativity can cause delocalization effects, where the electron cloud for a given bond expands to more than two atoms within the molecule.