Question

The maximum limits of
residual solvents during
microencapsulation for
chloroform and DCM
imposed by the 2002
edition of the USP and the
guidelines of the ICH​

Answer 1

Answer:

60 and 600ppm

Explanation:

Answer 2

Answer:

The maximum limits of residual solvents during microencapsulation for chloroform and DCM are 60 and 600 ppm.

Explanation:

• As per the edition of the USP and the guidelines of the ICH, the chloroform and DCM belong to Class 2 solvents and they are suspected of carcinogenic properties and also neurotoxicity.

• Health problems and environmental hazards are caused by DCH as well as from its products, so in order to protect human health and the environment, limiting the usage of these solvents is important.

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