Question

The oxy-hemoglobin dissociation curve shifts to the right by all the following except:

1) Increased carbon dioxide 2) Increased pH

3) Increased temperature 4) Presence of 2, 3 DPG​

Answer 1

Answer:

increase carbon dioxide in hemoglobin become deoxygenated blood

Answer 2

Answer:

Incorrect option is  (2) Increased pH

Explanation:

(a) Carbon dioxide has two effects on the curve: the Bohr effect and the accumulation of carbamino compounds produced by chemical reactions. Increased hydrogen ions keep haemoglobin in the T-state and cause oxygen unloading, which causes the dissociation curve to shift to the right.

(b) As the pH (acidity) decreases, the dissociation curve changes to the right, while as the pH (alkalinity) increases, the dissociation curve shifts to the left.

( c) The influence of temperature on the curve is simple to understand. At advanced temperatures, oxygen unloading is preferred, performing in a rightward shift. Lower temperatures, on the other hand, lead the dissociation curve to shift to the left.

(d) 2,3-Diphosphoglycerate (DPG) is a glycolysis intermediate product produced within the red blood cell that alters hemoglobin's oxygen affinity. The dissociation curve will shift to the right at high concentrations of 2,3-DPG, while the curve will shift to the left in low concentrations.

Incorrect option is  (2) Increased pH

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