Question

The pedigree above shows a cross between an affected female and unaffected male for Huntington's disease. Huntington's disease is autosomal dominant. If both parents have Huntington's disease, what are the chances that they will have children who do NOT have the disease

Answer 1

AS MENTIONED IN THE QUESTION HUTTINGTON DISEASE IS AUTOSOMAL DOMINANT AND EVEN IN THE PRESENCE OF SINGPE DOMINANT ALLELE THE TRAIT IS EXPRESSED.IF BOTH THE PARENTS ARE HETEROZYGOUS THEN 25%OF THEIR PROGENY IS UNAFFECTED.EVEN IF ONE OF THE PARENTS IS HOMOZYGOUS THEN COMPLETE PROGENY WILL BE EFFECTED BY THE DISEASE.

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