Question

The role of epigenetics in drug resistance in cancer

Answer 1

Answer:

Explanation:It has been observed experimentally that epigenetic phenomenon can induce temporary or reversible drug resistance phenotypes in cancer cell populations. Eg changes in methylation status of DNA repair genes may impact the responsivness of cells to chemotherapies. Although this phenomenon may be transient they can have lasting impact on the genetic evolution of tumour.

Short term epigentics may be serve as temporary lifelines for population until more permanent genetics resistance mechanism can be established