The sequence of DNA is 5’-ATGGTTCCATC-3’. What is the sequence of the complimentary
RNA strand?
Answers
DNA is a two-stranded molecule. Each strand is a polynucleotide composed of A (adenosine), T (thymidine), C (cytidine), and G (guanosine) residues polymerized by "dehydration" synthesis in linear chains with specific sequences. Each strand has polarity which runs from 5′ to 3′.
In DNA, A pirs with T and G pairs with C.
Fo through the original 5′ to 3′ sequence pairing each A with T ad each C wth G.
While RNA is a single strand molecule. This Strand also consists polynucleotide composed A, C, G and U (uridine).
For a complementary strand replace A with U (because RNA does not consist T), T with A, C with G, and G with C.
Hence,
Given strand: 5′ATGGTTCCATC3′
Complementary RNA strand: 3′UACCAAGGUAG5′
Keep in mind that the complementary strand will read from left to right in the 3 to 5 direction.