The Tumor microenvironment is often acidic than that of the normal tissues. Which amino acid on a
membrane protein would attract more anions (such as chloride ion) in the acidified tumor
microenvironment than in the normal environment?
S
Y
Н
D
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I don't no the answer sorry
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Option 3 H will attract anions.
Anions are negatively charged ions. Negatively charged ions can bind only to positively charged groups, which is present in basic amino acid.
Histidine contains positively charged basic side chain and hence can bind to chloride ions.
Out of other given amino acids, aspartic acid is polar and acidic amino acid. Tyrosine and serine are polar and neutral amino acids.
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