Question

Thymol column chromatography silica column

Answer 1

have identified carvacrol and thymol via thin-layer-chromatography and via gas chromatography On a normal silica plate the thymol has a higher Rf-value then carvacrol. The explanation for this would be the position of the hydroxyl-group and the difference size of the nearby methyl or isopropyl group. I think thymol should be more hydrophobic then carvacrol, explaining the less interaction with the silica gel resulting in a higher Rf-value