Question

Tissue like utilize only glucose to meets its need of energy

Answer 1

Each Organ Has a Unique Metabolic Profile

The metabolic patterns of the brain, muscle, adipose tissue, kidney, and liver are strikingly different.

Glucose is virtually the sole fuel for the human brain, except during prolonged starvation. The brain lacks fuel stores and hence requires a continuous supply of glucose.

Answer 2

Answer:

The required answer is shown below:

Explanation:

• In order to maintain homeostatic control of blood glucose levels, a family of facilitative glucose transporters (GLUTs) is involved in regulating tissue-specific glucose uptake and metabolism in the liver, skeletal muscle, and adipose tissue. Reduced glucose transport activity causes an abnormal utilization of energy substrates and is linked to type 2 diabetes and insulin resistance. It is well known that two key players in the regulation of whole-body glycemia are GLUT2, the principal controller of hepatic hexose flux, and GLUT4, the powerhouse of insulin- and contraction-stimulated glucose uptake in skeletal muscle.

• The relationship between poorer glycemic control in type 2 diabetes and the molecular mechanism by which insulin regulates glucose transport across membranes is still poorly understood. In response to a changed energy requirement, a variety of circulating metabolites, hormone-like compounds, and possibly additional glucose transporters all contribute to fine-tuning glucose transit between the various organs.

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