Question

Topical delivery of sirna-based spherical nucleic acid nanoparticle conjugates for gene regulation

Answer 1

Auxins (plural of auxin /ˈɔːksɪn/) are a class of plant hormones (or plant growth regulators) with some morphogen-like characteristics. Auxins have a cardinal role in coordination of many growth and behavioral processes in the plant's life cycle and are essential for plant body development. Auxins and their role in plant growth were first described by the Dutch biologist Frits Warmolt Went. Kenneth V. Thimann was the first to isolate one of these phytohormones and determine its chemical structure as indole-3-acetic acid (IAA). Went and Thimann co-authored a book on plant hormones, Phytohormones, in 1937.

Answer 2

Explanation:

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RNA interference is the mechanism of gene silencing or gene regulation in eukaryotes.

in case if a virus attack on cell.

As we know that mostly viruses have ds-RNA.

⚡⚡ Transcription occurs only in one strand .

So it reverses the polarity of strand so that it will be easy to transcript both strands.

⚡⚡Now it become double standard DNA.

(DICER) an enzyme it cut double-stranded dna into small fragments.

⚡⚡Now the siRNA i.e small interfering rna, convert that ds -rna of virus into ss-rna and store it to use it as a memory .

Here enzyme (Risc) is used.

⚡⚡ When further that virus attack then this ss-rna (stored) become complimentary to its rna ... Which acts as a foreign agent for cell and get destroyed.

I tried to explain as much as i can...

Hope it will help you.

#phoenix