Toxic substance responsible for fever and chill malaria
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PATHOGENESIS :- The fever and chills of malaria are associated with the rupture of erythrocytic-stage schizonts.
In severe falciparum malaria, parasitized red cells may obstruct capillaries and postcapillary venules, leading to local hypoxia and the release of toxic cellular products.
In severe falciparum malaria, parasitized red cells may obstruct capillaries and postcapillary venules, leading to local hypoxia and the release of toxic cellular products.
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Answer:haemozoic
Explanation:
During the rosette stage in paramecium the product of fission-merozoites come to lie near the membrane .the left over cytoplasm containing the Hematin granules ,metabolic waste called hemozoic is released into the plasma which causes the chills and fever
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