Question

Two anti-clotting factors found in the blood

Answer 1

Explanation:

Anticlotting mechanisms are important in restricting clot formation to the site of injury. The two major systems are the anticoagulant and fibrinolytic systems.

The anticoagulant system comprises four enzyme pathways whose function is to reduce thrombin production, limit its activity, or both.

Plasmin is the major enzyme of the fibrinolytic system and will ‘dissolve’ already formed clots by degrading fibrin.

Diseases of the anticoagulant system may be inherited or acquired and predispose to thromboembolic events.

Inherited disorders of the fibrinolytic system are very rare. The clinician is more likely to encounter acquired hyperfibrinolysis that can cause severe haemorrhage.