Two slides showing section of bone and cartilage are shown under microscope. How will you identify the two slides??
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Cartilage is a flexible connective tissue that differs from bone in several ways. For one, the primary cell types are chondrocytes as opposed to osteocytes. Chondrocytes are first chondroblast cells that produce the collagen extracellular matrix (ECM) and then get caught in the matrix. They lie in spaces called lacunae with up to eight chondrocytes located in each.
Chondrocytes rely on diffusion to obtain nutrients as, unlike bone, cartilage is avascular, meaning there are no vessels to carry blood to cartilage tissue. This lack of blood supply causes cartilage to heal very slowly compared with bone.
The base substance of cartilage is chondroitin sulfate, and the microarchitecture is substantially less organized than in bone. The cartilage fibrous sheath is called the perichondrium. The division of cells within cartilage occurs very slowly, and thus growth in cartilage is usually not based on an increase in size or mass of the cartilage itself.
Articular cartilage function is dependent on the molecular composition of its ECM, which consists mainly of proteoglycans and collagens. The remodeling of cartilage is predominantly affected by changes and rearrangements of the collagen matrix, which responds to tensile and compressive forces experienced by the cartilage.