Question

Unit 1 | Part - C
024. A protein in 100 mM KCl solution was heated and the observed T (midpoint of unfolding) was 60°C. When the
same protein solution in 500 mM KCl was heated, the observed To was 65°C. What is the most probable reason
for this increase in T?
a. Hydrogen-bonding is increased.
b. Hydrophobic interaction is decreased and electrostatic repulsion is increased.
c. Hydrophobic interaction is increased and electrostatic repulsion is decreased.
d. van der Waals interaction is increased.
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Answer 1

Answer:

c. hydrophobic interaction is increased and electrostatic repulsion is decreased