unqual duration during the summer solstice? Complete the given table about solstices and equinoxes. G. Date Part inclined towards the Sun Sunrays vertical at Longest day Shortest day Summer solstice North Pole Northern hemisphere 22nd December Winter solstice Tropic of Capricorn Northern hemisphere Equator Spring equinox 23rd September Equator Autumnal Equinox
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In popular perception and practice, centuries are structured by grouping years based on sharing the 'hundreds' digit(s). In this model, the 'n' -th century starts with the year that ends in "00" and ends with the year ending in "99"; for example, the years 1900 to 1999, in popular culture, constitute the 20th century
In this paper work, four naked nanocrystals (size range 80–700 nm) were prepared without any surfactant or polymer using the solvent/nonsolvent method. The effects of particle size on their solubility, dissolution, and oral bioavailability were investigated. Solubility and dissolution testing were performed in three types of dissolution medium, and the studies demonstrated that the equilibrium solubilities of coenzyme Q10 nanocrystals and bulk drugs were not affected by the dissolution media but the kinetic solubilities were. Kinetic solubility curves and changes in particle size distribution were determined and well explained by the proposed solubilization model for the nanocrystals and bulk drugs. The particle size effect on dissolution was clearly influenced by the diffusion coefficients of the various dissolution media, and the dissolution velocity of coenzyme Q10 increased as particle size decreased. The bioavailability of coenzyme Q10 after oral administration in beagle dogs was improved by reducing the particle size. For 700 nm nanocrystals, the AUC0–48 was 4.4-fold greater than that for the coarse suspensions, but a further decrease in particle size from 700 nm to 120 nm did not contribute to improvement in bioavailability until the particle size was reduced to 80 nm, when bioavailability was increased by 7.3-fold.