Question

upon which of the antibiotic factories composite in process dependent
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Answer 1

Explanation:

Drug Susceptibility

With all you've learned about bacteria and other microbes, it might seem almost like they're supernatural beings or something. They have virulence factors that help them set up infections better, they have ways to hide from our immune system, and they even have tons of ways to resist the antibiotics and other drugs that we throw at them. This lesson is about finding microbes' weak spots: finding out which antibiotics a particular microbe is especially susceptible to and exactly how much of a drug is needed so that we can destroy it and all its little buddies as soon as possible.

Diffusion Tests

As we've learned in other lessons in this chapter, different kinds of drugs work better for different kinds of organisms. If the organism causing an infection is known, doctors can choose an appropriate drug pretty easily. But often, the organism is unknown. Or it could be a type of bacteria that is often antibiotic-resistant. In these cases, it's a good idea to test which antibiotics it is susceptible to.

The first way we'll talk about is called the disk diffusion test / Kirby-Bauer test. First, you take your microbe of choice - for example, one that you've cultured out of a patient's infected lung. You spread a large amount of this microbe all over an agar plate in a Petri dish. There should be enough bacteria there that they'd cover the entire plate after you let them incubate at body temperature for a while.

But before you incubate them, you need to place a few paper disks that contain known amounts of various antibiotics on the plate. The drugs are going to diffuse gradually out of the disks and into the agar, hence the name 'diffusion test.' The further away from a disk you get, the lower the concentration of antibiotic will be there.